Recent Publications

Last updated 8/8 (2022)

  • Publications in Japanese


    Tsuji, A., Yamashita, H,, Osamu Hisatomi, O., Abe, M. (2022)
    Dimerization processes for light]regulated transcription factor Photozipper visualized by high]speed atomic force microscopy
    Scientific Reports, 12:12903. doi: 10.1038/s41598-022-17228-6

    Nakajima, H., Kobayashi, I., Adachi, Y., Hisatomi, O.* (2021)
    Transmission of light signals from the light-oxygen-voltage core via the hydrophobic region of the ƒĄ-sheet surface in aureochrome-1.
    Scientific Reports, 11: 11995. doi: 10.1038/s41598-021-91497-5

    Kobayashi, I., Nakajima, H., Hisatomi, O.* (2020)
    Molecular mechanism of light-induced conformational switching of the LOV domain in Aureochrome]1
    Biochemistry, 59(28), 2592-2601. doi: 10.1021/acs.biochem.0c00271

    Tateyama, S., Kobayashi, I., Hisatomi, O.* (2018)
    Target sequence recognition by a light-activatable bZIP factor, Photozipper.
    Biochemistry, 57(47), 6615-6623. doi: 10.1021/acs.biochem.8b00995

    Tsukuno, H., Ozeki, K., Kobayashi, I., Hisatomi, O.* and Mino, H.* (2018)
    Flavin radical Formation in the light-oxygen-voltage-sensing domain of the photozipper blue-light sensor protein.
    J Phys Chem B. 122(38):8819-8823. doi: 10.1021/acs.jpcb.8b05808

    Nakatani, Y. and Hisatomi, O. (2018)
    Quantitative analyses of the equilibria among DNA complexes of a blue-light-regulated bZIP module, Photozipper.
    Biophys. Physcobiol., 15, 8?17 (2018) doi: 10.2142/biophysico.15.0_8.

    Ozeki. K., Tsukuno, H., Nagashima, H., Hisatomi, O. and Mino, H, (2018)
    Dimeric structure of the blue light sensor protein photozipper in the activestate.
    Biochemistry 57(5):494-497. doi: 10.1021/acs.biochem.7b01045.

    Kojima, K., Matsutania, Y., Yamashita, T., Yanagawa, M., Imamoto, Y., Yamano, Y., Wada, A., Hisatomi, O., Nishikawa, K., Sakurai, K., Shichida, Y.* (2017)
    Adaptation of cone pigments found in green rods for scotopic vision through a single amino acid mutation.
    Proc. Natl. Acad. Sci. USA, 114(21), 5437-5442.

    Akiyama, Y., Nakasone, Y., Nakatani, Y., Hisatomi, O., Terazima, M.* (2016)
    Time-resolved Detection of Light-induced Dimerization of Monomeric Aureochrome-1 andChange in Affinity for DNA.
    J. Phys. Chem. B. 120, 7360-7370. doi:10.1021/acs.jpcb.6b05760

    Hisatomi O., Furuya, K. (2015)
    A light-regulated bZIP module, Photozipper, induces the binding of fused proteins to the target DNA sequence in a blue light-dependent manner.
    Photochem. Photobiol. Sci., 14, 1998-2006 doi: 10.1039/c5pp00178a.

    Nakatani Y, Hisatomi O (2015)
    Molecular mechanism of Photozipper, a light-regulated dimmerizing module consisting of bZIP and LOV domains of Aureochrome-1.
    Biochemistry 54, 3302-3313. doi: 10.1021/acs.biochem.5b00320.

    Hisatomi O, Nakatani Y, Takeuchi K, Takahashi F, Tokutomi S, Kataoka H. (2014)
    Blue Light-induced Dimerization of Monomeric Aureochrome-1 Enhances Its Affinity for the Target Sequence.
    J. Biol. Chem. 289, 17379-17391. doi: 10.1074/jbc.M114.554618

    Takeuchi, K. , Nakatani, Y. and Hisatomi, O. (2014)
    Accuracy of Protein Size Estimates Based on Light Scattering Measurements.
    Open Journal of Biophysics, 4, 83-91. doi: 10.4236/ojbiphy.2014.

    Hisatomi O, Takeuchi K, Zikihara K, Ookubo Y, Nakatani Y, Takahashi F, Tokutomi S, Kataoka H. (2013)
    Blue light-induced conformational changes in a light-regulated transcription factor, aureochrome-1.
    Plant Cell Physiol., 54(1), 93-106. doi: 10.1093/pcp/pcs160

    Goto,,Y., Tokunaga, F., Hisatomi, O. (2012)
    Hematological- and Neurological-expressed Sequence 1 Gene Products in Progenitor Cells during Newt Retinal Development.
    "Stem Cells International, vol. 2012, Article ID 436042, 6 pages, 2012. doi:10.1155/2012/436042. Reconciling Stem Cell Fate Decision with Tissue Organization" (ed. By Mark LaBarge) Jun 6

    Toyooka, T., Hisatomi, O., Takahashi, F., Kataoka, H., Terazima, M. (2011)
    Photoreactions of Aureochrome-1.
    Biophysical Journal, Biophys J., 100(11), 2801-2809 (2011) Jun 8

    Kataoka, Y., Kitadai, N., Hisatomi, O., Nakashima, S. (2011)
    Hydrogen bonding natures of water molecules in aqueous solutions of glycerol by Attenuated Total Reflection Infrared spectroscopy.
    Applied spectroscopy, 65(4), 436-441.

    Tsuchihara, K., Wazawa, T., Ishii, Y., Yanagida, T., Nishida, R., X-G Zheng, Ishiguro, M., Yoshihara, K., Hisatomi, O. and Tokunaga, F. (2009)
    Characterization of chemoreceptive protein binding to an oviposition stimulant using a fluorescent micro-binding assay in a butterfly.
    FEBS Lett., 583 (2), 345-349.

    Tsuchihara K, Hisatomi O, Tokunaga F, Asaoka K. (2009)
    An oviposition stimulant binding protein in a butterfly: Immunohistochemical localization and electrophysiological responses to plant compounds.
    Commun. Integr. Biol., 2(4), 356-358.

    Hasegawa, A., Tatsushi G., Hasegawa, K., Kobayashi, Y., Yamamoto, S., Kobayashi, H., Komaya, R., Tokunaga, F., and Hisatomi, O. (2008)
    Comparison of genes expressed in normal and regenerating newt retinas.
    In: gStrategies for Retinal Tissue Repair and Regeneration in Vertebrates: from Fish to Human" ed. By Chikafumi Chiba, Research Signpost, India

    Yamamoto, S., Hisatomi, O., Hasegawa, A., Kobayashi, Y. and Tokunaga, F. (2007)
    Distribution and Translocation of Photoreceptor G??-phosducin System in Medaka Retina.
    Photochem. Photobiol., 83, 35?39

    Imanishi, Y., Hisatomi, O., Yamamoto, S., Satoh, T., Kotaka, S., Kobayashi, Y. and Tokunaga, F. (2007)
    A third photoreceptor specific GRK found from Oryzias latipes (Japanese killifish) retina.
    Zool. Sci., 24 (1),õ87-93

    Hasegawa, A., Hisatomi, O., Yamamoto, S., Ono, E., and Tokunaga, F. (2007)
    Stathmin expression during newt retina regeneration.
    Exp. Eye Res., 85/4, 518-527.

    Goto, T., Hisatomi, O., Kotoura, M., Tokunaga, F. (2006)
    Induced expression of Hematopoietic- and neurologic-expressed sequence 1 in retinal pigment epithelial cells during newt retina regeneration.
    Exp. Eye Res., 83(4), 972-980.

    Ban, E., Kasai, A., Sato, M., Yokozeki, A., Hisatomi, O. and Oshima, N. (2005)
    The signaling pathway in photoresponses that may be mediated by visual pigments in erythrophores of Nile tilapia.
    Pigment Cell Res., 18, 360-369.

    Sakami, S., Hisatomi, O., Sakakibara, S. Liu, J. Reh, T. A. and Tokunaga, F. (2005)
    Downregulation of Otx2 in the dedifferentiated RPE cells of regenerating newt retina.
    Dev. Brain Res. 155(1), 49-59.

    Kobayashi, Y., Hisatomi, O. and Tokunaga, F. (2004)
    Phosphorylation of teleost phosducins and its effect on the affinity to G-protein beta gamma subunits.
    Biochem. Biophys. Res. Commun. 322(2), 477-482.

    Hisatomi, O. and Tokunaga, F. (2002) Molecular evolution of proteins involved in vertebrate phototransduction. (review)
    Comp. Biochem. Physiol. (in Comparetive Genomics, ed. Patrick J. Walsh) 133B, 509-522.

    Sakakibara, S., Hiramatsu, H., Takahashi, Y., Hisatomi, O., Kobayashi, Y., Sakami, S., Saito, T. and Tokunaga, F. (2002)
    Opsin expression in adult, developing, and regenerating newt retinas.
    Mol. Brain Res. vol 103, 28-35.

    Kobayashi, Y., Hisatomi, O., Yamamoto, S. and Tokunaga, F. (2002)
    Distribution of rod- and cone-specific phosducins in retinas of non-mammalian vertebrates.
    Comp. Biochem. Physiol. 133B, 77-83.

    Honkawa, H., Hisatomi, O., Kishida, Y. and Tokunaga, F. (2002)
    Two kinds of guanylate cyclase activating proteins in medaka retina
    Interdisciplinary Information Science (Interdisciplinary Info. Sci.) 8(1), 25-32.

    Taniguchi, Y., Hisatomi, O., Yoshida, M. and Tokunaga, F. (2001)
    Pinopsin expressed in retinal photoreceptors of a diurnal gecko.
    FEBS Lett. 496(2/3), 69-74.

    Yoshikawa, T., Okano, T., Kokame, K., Hisatomi, O., Tokunaga, F., Oishi, T. and Fukada, Y. (2001)
    Immunohistochemical localization of opsins and alpha-subunit of transducins in the pineal complex and deep brain of the Japanese grass lizard, Takydromus tachydromoides
    Zool. Sci. 18(3), 325-330.

    Takahashi, Y., Hisatomi, O., Sakakibara, S., Tokunaga, F. and Tsukahara, Y. (2001)
    Distribution of blue-sensitive photoreceptors in amphibian retinas.
    FEBS Lett. 501(2-3), 151-155.

    Imamoto, Y., Koshimizu,H., Mihara, K., Hisatomi, O., Mizukami, T., Tsujimoto, K., Kataoka, M., Tokunaga, F. (2001)
    Roles of Amino Acid Residues near the Chromophore of Photoactive Yellow Protein.
    Biochemistry 40(15), 4679-4685.

    Kobayashi, Y., Hisatomi, O., Satoh, T. and Tokunaga, F. (2001)
    Identification of phosducins expressed in teleost retinas.
    FEBS Lett. 502(3), 117-121

    Hisatomi O, Tokunaga F. (2000)
    Molecular basis for the evolution of teleost vision
    Tanpakushitsu Kakusan Koso. 2000 Dec;45(17 Suppl):2924-2930 (in Japanese)

    Tokunaga, F., Hisatomi, O., Satoh, T., Taniguchi, Y., Matsuda, S., Imanishi, Y., Honkawa, H., Takahashi, Y., Kobayashi, Y., Yoshida, M. and Tsukahara, Y. (1999)
    Evolution of visual pigments and related molecules. in Rhodopsins and phototransduction.
    (Novartis Foundation Symposium 224) pp 44-53, Wiley, Chichester.

    Imanishi, Y., Hisatomi, O. and Tokunaga, F. (1999)
    Two types of arrestins expressed in medaka rod photoreceptors
    FEBS Lett. 462(1-2), 31-36.

    Hisatomi, O., Takahashi, Y., Taniguchi, Y., Tsukahara, Y. and Tokunaga, F. (1999)
    Primary structure of a visual pigment in bullfrog green rods
    FEBS Lett. 447(1), 44-48.

    Hisatomi, O., Honkawa, H., Imanishi, Y., Satoh, T. and Tokunaga, F. (1999)
    Three kinds of guanylate cyclase expressed in medaka photoreceptor cells in both retina and pineal organ
    BBRC 255(2), 216-220.

    Taniguchi, Y., Hisatomi, O., Yoshida, M. and Tokunaga, F. (1999)
    Evolution of visual pigments in geckos.
    FEBS Lett. 445(1), 36-40.

    Yashiro, Y., Hisatomi, O., Tokunaga, F., Takenaka, O., Aimi, M. and Oishi, T. (1999)
    Divergence of primate visual pigments.
    Recent Advances in Physiological Anthropologyied. M. Sato, H. Tokura and S. Watanukij Kyushu University Press. pp 25-31.

    Matsuda, S., Hisatomi, O. and Tokunaga, F. (1999)
    Role of carboxyl-terminal charges on S-modulin membrane affinity and inhibition of rhodopsin phosphorylation.
    Biochemistry 38(4), 1310-1315.

    Matsuda, S., Hisatomi, O., Ishino, T., Kobayashi, Y. and Tokunaga, F. (1998)
    The Role of Calcium-Binding Sites in S-modulin Function.
    J. Biol. Chem. 273(32), 20223-20227.

    Hisatomi, O., Kayada, S., Taniguchi, Y., Kobayashi, Y., Satoh, T., and Tokunaga, F. (1998)
    Primary structure and characterization of a bullfrog visual pigment contained in small single cones.
    Comparative Biochemistry and Physiology, 119B, 585-591.

    Hisatomi, O., Matsuda, S., Satoh, T., Kotaka, S., Imanishi, Y. and Tokunaga, F. (1998)
    A novel subtype of G-protein-coupled receptor kinase, GRK7, in teleost cone photoreceptors.
    FEBS Lett. 424(3), 159-164.

    Osamu HISATOMI and Fumio TOKUNAGA (1998)
    Molecular evolution in photo-transduction system
    @Biophysics 38(1), 4-8. (in Japanese)

    Hisatomi, O., Ishikawa, M., Tonosaki, A. and Tokunaga, F. (1997)
    Characterization of lamprey rhodopsin by isolation from lamprey retina and expression in mammalian cells.
    Photochem. Photobiol. 66(6), 792-795.

    Hisatomi, O., Satoh, T. and Tokunaga, F. (1997)
    The primary structure and distribution of killifish visual pigments.
    Vision Res. 37(22), 3089-3096.

    Hisatomi, O., Imanishi, Y., Satoh, T. and Tokunaga, F. (1997)
    Arrestins expressed in killifish photoreceptor cells.
    FEBS Lett. 411(1), 12-18.

    Hisatomi, O., Ishino, T., Matsuda, S.,Yamaguchi, K., Kawamura, S. and Tokunaga, F. (1997)
    Functional expression and characterization of frog photoreceptor-specific calcium-binding proteins.
    Biochem. Biophys. Res. Commun. 234(1), 173-177.

    Imamoto, Y., Mihara, K., Shirahige, Y., Hisatomi, O., Kataoka, M., Tokunaga, F., Bojkova, N. and Yoshihara, K. (1997)
    First evidence for proton transfer from Glu-46 to the chromophore during the photocycle of photoactive yellow protein.
    J. Biol. Chem. 272(20), 12905-12908.

    Mihara, K., Hisatomi, O., Imamoto, Y., Kataoka, M. and Tokunaga, F. (1997)
    Functional expression and site-directed mutaganesis of photoactive yellow protein.
    J. Biochem. 121(5), 876-880

    Kawamura, S., Kuwata, O., Yamada, M., Matsuda, S., Hisatomi, O. and Tokunaga, F. (1996)
    Photoreceptor protein s26, a cone homologue of S-modulin in frog retina.
    J. Biol. Chem. 271(35), 21359-21364.

    Ishikawa, M., Tonosaki, A., Hisatomi, O., Tokunaga, F., Koseki, T. and Sakuragi, S. (1996)
    Lectin cytochemical analysis of glycoconjugates in photoreceptor cell membranes of Lampetra japonica.
    Vision Res. 36(11), 1513-1520.

    Stenkamp, D. L., Hisatomi, O., Barthel, L. K., Tokunaga, F. and Raymond, P. A. (1996)
    Temporal expression of rod and cone opsins in embryonic goldfish retina predicts the spatial organization of the cone mosaic.
    Invest. Ophthalmol. Vis. Sci. 37(2), 363-376.

    Sakamoto, K., Hisatomi, O., Tokunaga, F. and Eguchi, E. (1996)
    Two opsins from the compound eye of the crab, Hemigrapsus sanguineus.
    J. Exp. Biol. 199(2), 441-450.

    Kojima, D., Oura, T., Hisatomi, O., Tokunaga, F., Fukada, Y., Yoshizawa, T. and Shichida, Y.(1996)
    Molecular properties of chimerical mutants of gekko blue and bovine rhodopsin.
    Biochemistry 35(8), 2625-2629.

    Hisatomi, O., Satoh, T., Barthel, L. K., Stenkamp, D. L., Raymond, P. A. and Tokunaga, F. (1996)
    Molecular cloning and characterization of the putative ultraviolet-sensitive visual pigment of goldfish.
    Vision Res. 36(7), 933-939.



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